| Host: | Rabbit |
| Applications: | IHC/WB |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-SLC25A15 (N-Term) is suitable for use in Immunohistochemistry and Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Lyophilised |
| Purification: | IgG purified |
| Dilution Range: | IHC, WB (confirmed by recombinant protein). A dilution of 1: 200 to 1: 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications. |
| Storage Instruction: | Maintain the lyophilised/reconstituted antibodies frozen at-20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, Glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles. |
| Gene Symbol: | SLC25A15 |
| Gene ID: | 10166 |
| Uniprot ID: | ORNT1_HUMAN |
| Immunogen Region: | N-Term |
| Specificity: | Specific for SLC25A15. |
| Immunogen: | A synthetic peptide from n-terminal region of human SLC25A15 conjugated to blue carrier protein was used as the antigen. |
| Function | Mitochondrial ornithine-citrulline antiporter (Probable). Catalyzes the exchange between cytosolic ornithine and mitochondrial citrulline plus an H(+), the proton compensates the positive charge of ornithine thus leading to an electroneutral transport. Plays a crucial role in the urea cycle, by connecting the cytosolic and the intramitochondrial reactions of the urea cycle (Probable). Lysine and arginine are also transported by the antiport mechanism (Probable). In addition, catalyzes an electroneutral exchange of ornithine or lysine for H(+), a reaction driven by the pH gradient across the inner membrane. |
| Protein Name | Mitochondrial Ornithine Transporter 1Solute Carrier Family 25 Member 15 |
| Database Links | Reactome: R-HSA-70635 |
| Cellular Localisation | Mitochondrion Inner MembraneMulti-Pass Membrane ProteinMitochondrion Membrane |
| Alternative Antibody Names | Anti-Mitochondrial Ornithine Transporter 1 antibodyAnti-Solute Carrier Family 25 Member 15 antibodyAnti-SLC25A15 antibodyAnti-ORC1 antibodyAnti-ORNT1 antibodyAnti-SP1855 antibody |
Information sourced from Uniprot.org