Anti-SLC25A13 antibody (1-300) (STJ114431)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal SLC25A13 (1-300) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | SLC25A13 |
| Gene ID | 10165 |
| Uniprot ID | S2513_HUMAN |
| Immunogen Region | 1-300 |
| Immunogen Sequence | MAAAKVALTKRADPAELRTI FLKYASIEKNGEFFMSPNDF VTRYLNIFGESQPNPKTVEL LSGVVDQTKDGLISFQEFVA FESVLCAPDALFMVAFQLFD KAGKGEVTFEDVKQVFGQTT IHQHIPFNWDSEFVQLHFGK ERKRHLTYAEFTQFLLEIQL EHAKQAFVQRDNARTGRVTA IDFRDIMVTIRPHVLTPFVE ECLVAAAGGTTSHQVSFSYF NGFNSLLNNMELIRKIYST |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human SLC25A13 (NP_001153682.1). |
Additional Info
| Tissue Specificity | High levels in liver and low levels in kidney, pancreas, placenta, heart and brain. |
| Function | Mitochondrial electrogenic aspartate/glutamate antiporter that favors efflux of aspartate and entry of glutamate and proton within the mitochondria as part of the malate-aspartate shuttle. Also mediates the uptake of L-cysteinesulfinate (3-sulfino-L-alanine) by mitochondria in exchange of L-glutamate and proton. Can also exchange L-cysteinesulfinate with aspartate in their anionic form without any proton translocation. Lacks transport activity towards gamma-aminobutyric acid (GABA). |
| Protein Name | Electrogenic Aspartate/Glutamate Antiporter Slc25a13 - MitochondrialCalcium-Binding Mitochondrial Carrier Protein Aralar2Aralar-Related Gene 2Aralar2CitrinMitochondrial Aspartate Glutamate Carrier 2Solute Carrier Family 25 Member 13 |
| Database Links | Reactome: R-HSA-1268020Reactome: R-HSA-8963693Reactome: R-HSA-9856872 |
| Cellular Localisation | Mitochondrion Inner MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Electrogenic Aspartate/Glutamate Antiporter Slc25a13 - Mitochondrial antibodyAnti-Calcium-Binding Mitochondrial Carrier Protein Aralar2 antibodyAnti-Aralar-Related Gene 2 antibodyAnti-Aralar2 antibodyAnti-Citrin antibodyAnti-Mitochondrial Aspartate Glutamate Carrier 2 antibodyAnti-Solute Carrier Family 25 Member 13 antibodyAnti-SLC25A13 antibody |
Information sourced from Uniprot.org