| Host: | Rabbit |
| Applications: | IF/ICC/ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | SLC24A5 |
| Gene ID: | 283652 |
| Uniprot ID: | NCKX5_HUMAN |
| Immunogen Region: | 220-300 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 220-300 of human SLC24A5 (NP_995322.1). |
| Immunogen Sequence: | INQYIIKKCSPCCACLAKAM ERSEQQPLMGWEDEGQPFIR RQSRTDSGIFYEDSGYSQLS ISLHGLSQVSEDPPSVFNMP E |
| Function | Calcium, potassium:sodium antiporter that transports 1 Ca(2+) and 1 K(+) to the melanosome in exchange for 4 cytoplasmic Na(+). Involved in pigmentation, possibly by participating in ion transport in melanosomes. Predominant sodium-calcium exchanger in melanocytes. |
| Protein Name | Sodium/Potassium/Calcium Exchanger 5Na(+/K(+/Ca(2+-Exchange Protein 5Solute Carrier Family 24 Member 5 |
| Database Links | Reactome: R-HSA-425561Reactome: R-HSA-5619036 |
| Cellular Localisation | Golgi ApparatusTrans-Golgi Network MembraneMulti-Pass Membrane ProteinMelanosomeEnriched In Late-Stage Melanosomes |
| Alternative Antibody Names | Anti-Sodium/Potassium/Calcium Exchanger 5 antibodyAnti-Na(+/K(+/Ca(2+-Exchange Protein 5 antibodyAnti-Solute Carrier Family 24 Member 5 antibodyAnti-SLC24A5 antibodyAnti-JSX antibodyAnti-NCKX5 antibody |
Information sourced from Uniprot.org