Host: |
Rabbit |
Applications: |
IF |
Reactivity: |
Human |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-SLC24A5 (220-300) is suitable for use in Immunofluorescence research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
Purification: |
Affinity purification |
Dilution Range: |
IF/ICC 1:50-1:200 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
SLC24A5 |
Gene ID: |
283652 |
Uniprot ID: |
NCKX5_HUMAN |
Immunogen Region: |
220-300 |
Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 220-300 of human SLC24A5 (NP_995322.1). |
Immunogen Sequence: |
INQYIIKKCSPCCACLAKAM ERSEQQPLMGWEDEGQPFIR RQSRTDSGIFYEDSGYSQLS ISLHGLSQVSEDPPSVFNMP E |
Function | Calcium, potassium:sodium antiporter that transports 1 Ca(2+) and 1 K(+) to the melanosome in exchange for 4 cytoplasmic Na(+). Involved in pigmentation, possibly by participating in ion transport in melanosomes. Predominant sodium-calcium exchanger in melanocytes. |
Protein Name | Sodium/Potassium/Calcium Exchanger 5Na(+/K(+/Ca(2+-Exchange Protein 5Solute Carrier Family 24 Member 5 |
Database Links | Reactome: R-HSA-425561Reactome: R-HSA-5619036 |
Cellular Localisation | Golgi ApparatusTrans-Golgi Network MembraneMulti-Pass Membrane ProteinMelanosomeEnriched In Late-Stage Melanosomes |
Alternative Antibody Names | Anti-Sodium/Potassium/Calcium Exchanger 5 antibodyAnti-Na(+/K(+/Ca(2+-Exchange Protein 5 antibodyAnti-Solute Carrier Family 24 Member 5 antibodyAnti-SLC24A5 antibodyAnti-JSX antibodyAnti-NCKX5 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance