• Immunofluorescence analysis of Hela cells using SLC24A5 Rabbit polyclonal antibody (STJ117417) at dilution of 1:100 (40x lens). Secondary antibody: Cy3 Goat Anti-Rabbit IgG (H+L) at 1:500 dilution. Blue: DAPI for nuclear staining.

Anti-SLC24A5 antibody (220-300) (STJ117417)

SKU:
STJ117417

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Host: Rabbit
Applications: IF
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-SLC24A5 (220-300) is suitable for use in Immunofluorescence research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: IF/ICC 1:50-1:200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: SLC24A5
Gene ID: 283652
Uniprot ID: NCKX5_HUMAN
Immunogen Region: 220-300
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 220-300 of human SLC24A5 (NP_995322.1).
Immunogen Sequence: INQYIIKKCSPCCACLAKAM ERSEQQPLMGWEDEGQPFIR RQSRTDSGIFYEDSGYSQLS ISLHGLSQVSEDPPSVFNMP E
Function Calcium, potassium:sodium antiporter that transports 1 Ca(2+) and 1 K(+) to the melanosome in exchange for 4 cytoplasmic Na(+). Involved in pigmentation, possibly by participating in ion transport in melanosomes. Predominant sodium-calcium exchanger in melanocytes.
Protein Name Sodium/Potassium/Calcium Exchanger 5
Na(+/K(+/Ca(2+-Exchange Protein 5
Solute Carrier Family 24 Member 5
Database Links Reactome: R-HSA-425561
Reactome: R-HSA-5619036
Cellular Localisation Golgi Apparatus
Trans-Golgi Network Membrane
Multi-Pass Membrane Protein
Melanosome
Enriched In Late-Stage Melanosomes
Alternative Antibody Names Anti-Sodium/Potassium/Calcium Exchanger 5 antibody
Anti-Na(+/K(+/Ca(2+-Exchange Protein 5 antibody
Anti-Solute Carrier Family 24 Member 5 antibody
Anti-SLC24A5 antibody
Anti-JSX antibody
Anti-NCKX5 antibody

Information sourced from Uniprot.org

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