Host: |
Rabbit |
Applications: |
WB |
Reactivity: |
Human/Mouse/Rat |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-Sodium-dependent phosphate transporter 2 (370-420 aa) is suitable for use in Western Blot research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: |
1 mg/mL |
Dilution Range: |
WB 1:500-2000 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
SLC20A2 |
Gene ID: |
6575 |
Uniprot ID: |
S20A2_HUMAN |
Immunogen Region: |
370-420 aa |
Specificity: |
This antibody detects endogenous levels of S20A2 at Human/Mouse/Rat |
Immunogen: |
Synthesized peptide derived from the human S20A2 at the amino acid range 370-420 |
Function | Sodium-phosphate symporter which preferentially transports the monovalent form of phosphate with a stoichiometry of two sodium ions per phosphate ion. Plays a critical role in the determination of bone quality and strength by providing phosphate for bone mineralization. Required to maintain normal cerebrospinal fluid phosphate levels. Mediates phosphate-induced calcification of vascular smooth muscle cells (VCMCs) and can functionally compensate for loss of SLC20A1 in VCMCs. (Microbial infection) Functions as a retroviral receptor and confers human cells susceptibility to infection to amphotropic murine leukemia virus (A-MuLV), 10A1 murine leukemia virus (10A1 MLV) and some feline leukemia virus subgroup B (FeLV-B) variants. |
Protein Name | Sodium-Dependent Phosphate Transporter 2Gibbon Ape Leukemia Virus Receptor 2Glvr-2Phosphate Transporter 2Pit-2Pit2Hpit2Solute Carrier Family 20 Member 2 |
Database Links | Reactome: R-HSA-427652Reactome: R-HSA-5619111 |
Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinApical Cell Membrane |
Alternative Antibody Names | Anti-Sodium-Dependent Phosphate Transporter 2 antibodyAnti-Gibbon Ape Leukemia Virus Receptor 2 antibodyAnti-Glvr-2 antibodyAnti-Phosphate Transporter 2 antibodyAnti-Pit-2 antibodyAnti-Pit2 antibodyAnti-Hpit2 antibodyAnti-Solute Carrier Family 20 Member 2 antibodyAnti-SLC20A2 antibodyAnti-GLVR2 antibodyAnti-PIT2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance