Anti-SLC1A3 antibody (C-Term) (STJ13100122)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthetic peptide from c-terminal region of mouse SLC1A3 conjugated to blue carrier protein was used as the antigen. The peptide is homologous in rat.
General Information
| Short Description | Rabbit polyclonal anti-SLC1A3 (C-Term) for use in IHC and WB in Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC/WB |
| Host | Rabbit |
| Reactivity | Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | IgG purified |
| Dilution Range | IHC, WB. A dilution of 1:300 to 1:2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications. |
| Formulation | Lyophilised |
| Storage Instruction | Maintain the lyophilised/reconstituted antibodies frozen at-20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, Glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles. |
Target Information
| Gene Symbol | Slc1a3 |
| Gene ID | 20512 |
| Uniprot ID | EAA1_MOUSE |
| Immunogen | A synthetic peptide from c-terminal region of mouse SLC1A3 conjugated to blue carrier protein was used as the antigen. The peptide is homologous in rat. |
| Immunogen Region | C-Term |
| Specificity | Specific for EAAT1. |
Additional Info
| Post Translational Modifications | Glycosylated. |
| Function | Sodium-dependent, high-affinity amino acid transporter that mediates the uptake of L-glutamate and also L-aspartate and D-aspartate. Functions as a symporter that transports one amino acid molecule together with two or three Na(+) ions and one proton, in parallel with the counter-transport of one K(+) ion. Plays a redundant role in the rapid removal of released glutamate from the synaptic cleft, which is essential for terminating the postsynaptic action of glutamate. |
| Protein Name | Excitatory Amino Acid Transporter 1Glial High Affinity Glutamate TransporterHigh-Affinity Neuronal Glutamate TransporterGlut-1Sodium-Dependent Glutamate/Aspartate Transporter 1Glast-1Solute Carrier Family 1 Member 3 |
| Database Links | Reactome: R-MMU-210455Reactome: -MMU-210500Reactome: -MMU-425393 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Excitatory Amino Acid Transporter 1 antibodyAnti-Glial High Affinity Glutamate Transporter antibodyAnti-High-Affinity Neuronal Glutamate Transporter antibodyAnti-Glut-1 antibodyAnti-Sodium-Dependent Glutamate/Aspartate Transporter 1 antibodyAnti-Glast-1 antibodyAnti-Solute Carrier Family 1 Member 3 antibodyAnti-Slc1a3 antibodyAnti-Eaat1 antibodyAnti-Gmt1 antibody |
Information sourced from Uniprot.org