Anti-SLC10A2/ASBT antibody (C-Term) (STJ71674)
SPECIFICATIONS
ClonalityPolyclonal
HostGoat
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Goat polyclonal antibody anti-SLC10A2/ASBT (C-Term) is suitable for use in ELISA and Immunohistochemistry research applications. |
| Applications | Pep-ELISA/IHC |
| Host | Goat |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.5 mg/mL |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Dilution Range | Peptide ELISA: antibody detection limit dilution 1:16000.WB: Preliminary experiments gave an approx. 60kDa band in Human Kidney lysates after 0.1µg/ml antibody staining. Please note that currently we cannot find an explanation in the literature |
| Formulation | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Storage Instruction | Store at-20°C on receipt and minimise freeze-thaw cycles. |
Target Information
| Gene Symbol | SLC10A2 |
| Gene ID | 6555 |
| Uniprot ID | NTCP2_HUMAN |
| Accession Number | NP_000443.1 |
| Immunogen Region | C-Term |
| Immunogen Sequence | YKANGGFQPDEK |
Additional Info
| Function | Plays a critical role in the sodium-dependent reabsorption of bile acids from the lumen of the small intestine. Transports various bile acids, unconjugated or conjugated, such as cholate and taurocholate. Also responsible for bile acid transport in the renal proximal tubules, a salvage mechanism that helps conserve bile acids (Probable). Works collaboratively with the Na(+)-taurocholate cotransporting polypeptide (NTCP), the organic solute transporter (OST), and the bile salt export pump (BSEP), to ensure efficacious biological recycling of bile acids during enterohepatic circulation. |
| Protein Name | Ileal Sodium/Bile Acid CotransporterApical Sodium-Dependent Bile Acid TransporterAsbtIleal Na(+/Bile Acid CotransporterIleal Sodium-Dependent Bile Acid TransporterIbatIsbtNa(+-Dependent Ileal Bile Acid TransporterSodium/Taurocholate Cotransporting Polypeptide - IlealSolute Carrier Family 10 Member 2 |
| Database Links | Reactome: R-HSA-159418 |
| Cellular Localisation | MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Ileal Sodium/Bile Acid Cotransporter antibodyAnti-Apical Sodium-Dependent Bile Acid Transporter antibodyAnti-Asbt antibodyAnti-Ileal Na(+/Bile Acid Cotransporter antibodyAnti-Ileal Sodium-Dependent Bile Acid Transporter antibodyAnti-Ibat antibodyAnti-Isbt antibodyAnti-Na(+-Dependent Ileal Bile Acid Transporter antibodyAnti-Sodium/Taurocholate Cotransporting Polypeptide - Ileal antibodyAnti-Solute Carrier Family 10 Member 2 antibodyAnti-SLC10A2 antibodyAnti-ASBT antibodyAnti-ISBT antibodyAnti-NTCP2 antibody |
Information sourced from Uniprot.org