Anti-SLC10A2 antibody (46-96 aa) (STJ194132)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human NTCP2 at the amino acid range 46-96
General Information
| Short Description | Rabbit polyclonal anti-Ileal sodium/bile acid cotransporter/bile acid cotransporter-dependent ileal bile acid transporter (46-96 aa) for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | SLC10A2 |
| Gene ID | 6555 |
| Uniprot ID | NTCP2_HUMAN |
| Immunogen | Synthesized peptide derived from the human NTCP2 at the amino acid range 46-96 |
| Immunogen Region | 46-96 aa |
| Specificity | This antibody detects endogenous levels of NTCP2 at Human/Mouse/Rat |
Additional Info
| Function | Plays a critical role in the sodium-dependent reabsorption of bile acids from the lumen of the small intestine. Transports various bile acids, unconjugated or conjugated, such as cholate and taurocholate. Also responsible for bile acid transport in the renal proximal tubules, a salvage mechanism that helps conserve bile acids (Probable). Works collaboratively with the Na(+)-taurocholate cotransporting polypeptide (NTCP), the organic solute transporter (OST), and the bile salt export pump (BSEP), to ensure efficacious biological recycling of bile acids during enterohepatic circulation. |
| Protein Name | Ileal Sodium/Bile Acid CotransporterApical Sodium-Dependent Bile Acid TransporterAsbtIleal Na(+/Bile Acid CotransporterIleal Sodium-Dependent Bile Acid TransporterIbatIsbtNa(+-Dependent Ileal Bile Acid TransporterSodium/Taurocholate Cotransporting Polypeptide - IlealSolute Carrier Family 10 Member 2 |
| Database Links | Reactome: R-HSA-159418 |
| Cellular Localisation | MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Ileal Sodium/Bile Acid Cotransporter antibodyAnti-Apical Sodium-Dependent Bile Acid Transporter antibodyAnti-Asbt antibodyAnti-Ileal Na(+/Bile Acid Cotransporter antibodyAnti-Ileal Sodium-Dependent Bile Acid Transporter antibodyAnti-Ibat antibodyAnti-Isbt antibodyAnti-Na(+-Dependent Ileal Bile Acid Transporter antibodyAnti-Sodium/Taurocholate Cotransporting Polypeptide - Ileal antibodyAnti-Solute Carrier Family 10 Member 2 antibodyAnti-SLC10A2 antibodyAnti-ASBT antibodyAnti-ISBT antibodyAnti-NTCP2 antibody |
Information sourced from Uniprot.org