Anti-SLA2 antibody (159-209) (STJA0006628)

SKU:
STJA0006628
£48.00 - £252.00
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Host: Rabbit
Applications: WB
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Rabbit polyclonal antibody anti-Src-like-adapter 2 (159-209) is suitable for use in Western Blot research applications.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:1000-2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: SLA2
Gene ID: 84174
Uniprot ID: SLAP2_HUMAN
Immunogen Region: 159-209
Specificity: This antibody detects endogenous levels of human SLAP2
Immunogen: Synthesized peptide derived from human SLAP2 AA range: 159-209
Post Translational Modifications Phosphorylated by CSF1R.
Function Adapter protein, which negatively regulates T-cell receptor (TCR) signaling. Inhibits T-cell antigen-receptor induced activation of nuclear factor of activated T-cells. May act by linking signaling proteins such as ZAP70 with CBL, leading to a CBL dependent degradation of signaling proteins.
Protein Name Src-Like-Adapter 2
Modulator Of Antigen Receptor Signaling
Mars
Src-Like Adapter Protein 2
Slap-2
Database Links Reactome: R-HSA-9706369
Cellular Localisation Cytoplasm
Isoform 1: Cell Membrane
Cytoplasmic Vesicle
Localized To The Plasma Membrane And Intracellular Vesicles
Including Late Endosomal Vesicles
Isoform 2: Cytoplasm
May Be Cytoplasmic And Is Not Localized To Membranes
Alternative Antibody Names Anti-Src-Like-Adapter 2 antibody
Anti-Modulator Of Antigen Receptor Signaling antibody
Anti-Mars antibody
Anti-Src-Like Adapter Protein 2 antibody
Anti-Slap-2 antibody
Anti-SLA2 antibody
Anti-C20orf156 antibody
Anti-SLAP2 antibody

Information sourced from Uniprot.org

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