Anti-SKAP2 antibody (1-120) (STJ118195)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal SKAP2 (1-120) antibody for use in WB, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | SKAP2 |
| Gene ID | 8935 |
| Uniprot ID | SKAP2_HUMAN |
| Immunogen Region | 1-120 |
| Immunogen Sequence | MPNPSSTSSPYPLPEEIRNL LADVETFVADILKGENLSKK AKEKRESLIKKIKDVKSIYL QEFQDKGDAEDGEEYDDPFA GPPDTISLASERYDKDDEAP SDGAQFPPIAAQDLPFVLKA |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-120 of human SKAP2 (NP_003921.2). |
Additional Info
| Tissue Specificity | Ubiquitously expressed. Present in platelets (at protein level). |
| Post Translational Modifications | Phosphorylated in resting platelets. Phosphorylated by FYN on Tyr-261 upon T-cell activation (Probable). Dephosphorylated on Tyr-75 by PTPN22. |
| Function | May be involved in B-cell and macrophage adhesion processes. In B-cells, may act by coupling the B-cell receptor (BCR) to integrin activation. May play a role in src signaling pathway. |
| Protein Name | Src Kinase-Associated Phosphoprotein 2Pyk2/Raftk-Associated ProteinRetinoic Acid-Induced Protein 70Skap55 HomologSkap-55homSkap-HomSrc Family-Associated Phosphoprotein 2Src Kinase-Associated Phosphoprotein 55-Related ProteinSrc-Associated Adapter Protein With Ph And Sh3 Domains |
| Database Links | Reactome: R-HSA-391160 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Src Kinase-Associated Phosphoprotein 2 antibodyAnti-Pyk2/Raftk-Associated Protein antibodyAnti-Retinoic Acid-Induced Protein 70 antibodyAnti-Skap55 Homolog antibodyAnti-Skap-55hom antibodyAnti-Skap-Hom antibodyAnti-Src Family-Associated Phosphoprotein 2 antibodyAnti-Src Kinase-Associated Phosphoprotein 55-Related Protein antibodyAnti-Src-Associated Adapter Protein With Ph And Sh3 Domains antibodyAnti-SKAP2 antibodyAnti-PRAP antibodyAnti-RA70 antibodyAnti-SAPS antibodyAnti-SCAP2 antibodyAnti-SKAP55R antibody |
Information sourced from Uniprot.org