| Short Description : | Rabbit polyclonal SIGLEC9 (210-340) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Affinity purification |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | SIGLEC9 |
| Gene ID: | 27180 |
| Uniprot ID: | SIGL9_HUMAN |
| Immunogen Region: | 210-340 |
| Immunogen Sequence: | SLTCQVTFPGASVTTNKTVH LNVSYPPQNLTMTVFQGDGT VSTVLGNGSSLSLPEGQSLR LVCAVDAVDSNPPARLSLSW RGLTLCPSQPSNPGVLELPW VHLRDAAEFTCRAQNPLGSQ QVYLNVSLQSK |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 210-340 of human SIGLEC9 (NP_001185487.1). |
| Tissue Specificity | Expressed by peripheral blood leukocytes (neutrophils and monocytes but not eosinophils). Found in liver, fetal liver, bone marrow, placenta, spleen and in lower levels in skeletal muscle, fetal brain, stomach, lung, thymus, prostate, brain, mammary, adrenal gland, colon, trachea, cerebellum, testis, small intestine and spinal cordon. |
| Function | Putative adhesion molecule that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,3- or alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. |
| Protein Name | Sialic Acid-Binding Ig-Like Lectin 9Siglec-9Cdw329Protein Foap-9Cd Antigen Cd329 |
| Database Links | Reactome: R-HSA-198933Reactome: R-HSA-6798695 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Sialic Acid-Binding Ig-Like Lectin 9 antibodyAnti-Siglec-9 antibodyAnti-Cdw329 antibodyAnti-Protein Foap-9 antibodyAnti-Cd Antigen Cd329 antibodyAnti-SIGLEC9 antibodyAnti-UNQ668 antibodyAnti-PRO1302 antibody |
Information sourced from Uniprot.org
