Anti-SIGLEC15 antibody (20-263) (STJ11100588)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal SIGLEC15 (20-263) antibody for use in WB, IHC-P, IF, ICC and ELISA in human and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P/IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:1000IHC-P:1:50-1:200IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | SIGLEC15 |
| Gene ID | 284266 |
| Uniprot ID | SIG15_HUMAN |
| Immunogen Region | 20-263 |
| Immunogen Sequence | FVRTKIDTTENLLNTEVHSS PAQRWSMQVPPEVSAEAGDA AVLPCTFTHPHRHYDGPLTA IWRAGEPYAGPQVFRCAAAR GSELCQTALSLHGRFRLLGN PRRNDLSLRVERLALADDRR YFCRVEFAGDVHDRYESRHG VRLHVTAAPRIVNISVLPSP AHAFRALCTAEGEPPPALAW SGPALGNSLAAVRSPREGHG HLVTAELPALTHDGRYTCTA ANSLGRSEASVYLFRFHGA |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 20-263 of human Siglec-15 (NP_998767.1). |
Additional Info
| Tissue Specificity | Expressed in macrophage and/or dendritic cells of spleen and lymph nodes. |
| Function | Binds sialylated glycoproteins. |
| Protein Name | Sialic Acid-Binding Ig-Like Lectin 15Siglec-15Cd33 Antigen-Like 3 |
| Database Links | Reactome: R-HSA-2172127 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Sialic Acid-Binding Ig-Like Lectin 15 antibodyAnti-Siglec-15 antibodyAnti-Cd33 Antigen-Like 3 antibodyAnti-SIGLEC15 antibodyAnti-CD33L3 antibody |
Information sourced from Uniprot.org