| Host: | Rabbit |
| Applications: | WB/IHC-P/IF/ICC/ELISA |
| Reactivity: | Human/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:1000IHC-P:1:50-1:200IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | SIGLEC15 |
| Gene ID: | 284266 |
| Uniprot ID: | SIG15_HUMAN |
| Immunogen Region: | 20-263 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 20-263 of human Siglec-15 (NP_998767.1). |
| Immunogen Sequence: | FVRTKIDTTENLLNTEVHSS PAQRWSMQVPPEVSAEAGDA AVLPCTFTHPHRHYDGPLTA IWRAGEPYAGPQVFRCAAAR GSELCQTALSLHGRFRLLGN PRRNDLSLRVERLALADDRR YFCRVEFAGDVHDRYESRHG VRLHVTAAPRIVNISVLPSP AHAFRALCTAEGEPPPALAW SGPALGNSLAAVRSPREGHG HLVTAELPALTHDGRYTCTA ANSLGRSEASVYLFRFHGA |
| Tissue Specificity | Expressed in macrophage and/or dendritic cells of spleen and lymph nodes. |
| Function | Binds sialylated glycoproteins. |
| Protein Name | Sialic Acid-Binding Ig-Like Lectin 15Siglec-15Cd33 Antigen-Like 3 |
| Database Links | Reactome: R-HSA-2172127 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Sialic Acid-Binding Ig-Like Lectin 15 antibodyAnti-Siglec-15 antibodyAnti-Cd33 Antigen-Like 3 antibodyAnti-SIGLEC15 antibodyAnti-CD33L3 antibody |
Information sourced from Uniprot.org