Anti-SHC4 antibody (STJA0007830)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human SHC4
General Information
| Short Description | Rabbit polyclonal anti-SHC-transforming protein 4 for use in WB in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | SHC4 |
| Gene ID | 399694 |
| Uniprot ID | SHC4_HUMAN |
| Immunogen | Synthesized peptide derived from human SHC4 |
| Specificity | This antibody detects endogenous levels of SHC4 at Human, Mouse |
Additional Info
| Post Translational Modifications | Phosphorylated.the phosphorylation is enhanced by EGF. Phosphorylation at Tyr-424 is required for the interaction with GRB2. |
| Function | Activates both Ras-dependent and Ras-independent migratory pathways in melanomas. Contributes to the early phases of agrin-induced tyrosine phosphorylation of CHRNB1. |
| Protein Name | Shc-Transforming Protein 4Rai-Like ProteinRalpShc-Transforming Protein DHshcdSrc Homology 2 Domain-Containing-Transforming Protein C4Sh2 Domain Protein C4 |
| Database Links | |
| Cellular Localisation | Postsynaptic Cell MembraneColocalized With Musk At The Neuromuscular Junction |
| Alternative Antibody Names | Anti-Shc-Transforming Protein 4 antibodyAnti-Rai-Like Protein antibodyAnti-Ralp antibodyAnti-Shc-Transforming Protein D antibodyAnti-Hshcd antibodyAnti-Src Homology 2 Domain-Containing-Transforming Protein C4 antibodyAnti-Sh2 Domain Protein C4 antibodyAnti-SHC4 antibodyAnti-SHCD antibodyAnti-UNQ6438 antibodyAnti-PRO21364 antibody |
Information sourced from Uniprot.org