Host: | Rabbit |
Applications: | WB |
Reactivity: | Human/Mouse |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description : | Rabbit polyclonal antibody anti-SHC-transforming protein 4 is suitable for use in Western Blot research applications. |
Clonality : | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: | 1 mg/mL |
Dilution Range: | WB 1:500-2000 |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | SHC4 |
Gene ID: | 399694 |
Uniprot ID: | SHC4_HUMAN |
Specificity: | This antibody detects endogenous levels of SHC4 at Human, Mouse |
Immunogen: | Synthesized peptide derived from human SHC4 |
Post Translational Modifications | Phosphorylated.the phosphorylation is enhanced by EGF. Phosphorylation at Tyr-424 is required for the interaction with GRB2. |
Function | Activates both Ras-dependent and Ras-independent migratory pathways in melanomas. Contributes to the early phases of agrin-induced tyrosine phosphorylation of CHRNB1. |
Protein Name | Shc-Transforming Protein 4Rai-Like ProteinRalpShc-Transforming Protein DHshcdSrc Homology 2 Domain-Containing-Transforming Protein C4Sh2 Domain Protein C4 |
Cellular Localisation | Postsynaptic Cell MembraneColocalized With Musk At The Neuromuscular Junction |
Alternative Antibody Names | Anti-Shc-Transforming Protein 4 antibodyAnti-Rai-Like Protein antibodyAnti-Ralp antibodyAnti-Shc-Transforming Protein D antibodyAnti-Hshcd antibodyAnti-Src Homology 2 Domain-Containing-Transforming Protein C4 antibodyAnti-Sh2 Domain Protein C4 antibodyAnti-SHC4 antibodyAnti-SHCD antibodyAnti-UNQ6438 antibodyAnti-PRO21364 antibody |
Information sourced from Uniprot.org