Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue, using SHC3 Antibody. The picture on the right is blocked with the synthesized peptide.

Anti-SHC3 antibody (291-340) (STJ94561)

SKU:
STJ94561
£48.00 - £252.00
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Host: Rabbit
Applications: IHC/IF/ELISA
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Rabbit polyclonal antibody anti-SHC-transforming protein 3 (291-340) is suitable for use in Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: IHC 1:100-1:300
ELISA 1:10000
IF 1:50-200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: SHC3
Gene ID: 53358
Uniprot ID: SHC3_HUMAN
Immunogen Region: 291-340
Specificity: N-Shc Polyclonal Antibody detects endogenous levels of N-Shc protein.
Immunogen: The antiserum was produced against synthesized peptide derived from human SHC3. AA range:291-340
Tissue Specificity Mainly expressed in brain. Hardly detectable in other tissues, except in pancreas. Highly expressed in the cerebral cortex, frontal and temporal lobes, occipital pole, hippocampus, caudate nucleus and amygdala. Expressed at low level in the cerebellum, medulla and spinal cord.
Post Translational Modifications Tyrosine phosphorylated.
Function Signaling adapter that couples activated growth factor receptors to signaling pathway in neurons. Involved in the signal transduction pathways of neurotrophin-activated Trk receptors in cortical neurons.
Protein Name Shc-Transforming Protein 3
Neuronal Shc
N-Shc
Protein Rai
Shc-Transforming Protein C
Src Homology 2 Domain-Containing-Transforming Protein C3
Sh2 Domain Protein C3
Database Links Reactome: R-HSA-167044
Reactome: R-HSA-5673001
Reactome: R-HSA-8853659
Alternative Antibody Names Anti-Shc-Transforming Protein 3 antibody
Anti-Neuronal Shc antibody
Anti-N-Shc antibody
Anti-Protein Rai antibody
Anti-Shc-Transforming Protein C antibody
Anti-Src Homology 2 Domain-Containing-Transforming Protein C3 antibody
Anti-Sh2 Domain Protein C3 antibody
Anti-SHC3 antibody
Anti-NSHC antibody
Anti-SHCC antibody

Information sourced from Uniprot.org

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