Anti-SHANK1 antibody (N-Term) (STJA0005704)

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STJA0005704-100
$614.93
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Covered by St John's Laboratory Guarantee

Host: Rabbit
Applications: WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Rabbit polyclonal antibody anti-SHANK1a (N-Term) is suitable for use in Western Blot research applications.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS + 0.02% NaN3
Purification: Antigen Affinity Purified
Dilution Range: WB 1:500-1:1000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: SHANK1
Gene ID: 50944
Uniprot ID: SHAN1_HUMAN
Immunogen Region: N-Term
Specificity: Reacts with the N-terminal region of human, mouse and rat Shank1a protein.
Immunogen: Synthetic peptide corresponding to amino acids from the N-terminal region of human Shank1a protein
Function Seems to be an adapter protein in the postsynaptic density (PSD) of excitatory synapses that interconnects receptors of the postsynaptic membrane including NMDA-type and metabotropic glutamate receptors via complexes with GKAP/PSD-95 and Homer, respectively, and the actin-based cytoskeleton. Plays a role in the structural and functional organization of the dendritic spine and synaptic junction.
Protein Name Sh3 And Multiple Ankyrin Repeat Domains Protein 1
Shank1
Somatostatin Receptor-Interacting Protein
Sstr-Interacting Protein
Sstrip
Database Links Reactome: R-HSA-6794361
Cellular Localisation Cytoplasm
Postsynaptic Density
Synapse
Colocalizes With Alpha-Latrotoxin Receptor 1
Alternative Antibody Names Anti-Sh3 And Multiple Ankyrin Repeat Domains Protein 1 antibody
Anti-Shank1 antibody
Anti-Somatostatin Receptor-Interacting Protein antibody
Anti-Sstr-Interacting Protein antibody
Anti-Sstrip antibody
Anti-SHANK1 antibody

Information sourced from Uniprot.org

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