| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-SHANK1a (N-Term) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS + 0.02% NaN3 |
| Purification: |
Antigen Affinity Purified |
| Dilution Range: |
WB 1:500-1:1000IHCICCIP |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
SHANK1 |
| Gene ID: |
50944 |
| Uniprot ID: |
SHAN1_HUMAN |
| Immunogen Region: |
N-Term |
| Specificity: |
Reacts with the N-terminal region of human, mouse and rat Shank1a protein. |
| Immunogen: |
Synthetic peptide corresponding to amino acids from the N-terminal region of human Shank1a protein |
| Function | Seems to be an adapter protein in the postsynaptic density (PSD) of excitatory synapses that interconnects receptors of the postsynaptic membrane including NMDA-type and metabotropic glutamate receptors via complexes with GKAP/PSD-95 and Homer, respectively, and the actin-based cytoskeleton. Plays a role in the structural and functional organization of the dendritic spine and synaptic junction. |
| Protein Name | Sh3 And Multiple Ankyrin Repeat Domains Protein 1Shank1Somatostatin Receptor-Interacting ProteinSstr-Interacting ProteinSstrip |
| Database Links | Reactome: R-HSA-6794361 |
| Cellular Localisation | CytoplasmPostsynaptic DensitySynapseColocalizes With Alpha-Latrotoxin Receptor 1 |
| Alternative Antibody Names | Anti-Sh3 And Multiple Ankyrin Repeat Domains Protein 1 antibodyAnti-Shank1 antibodyAnti-Somatostatin Receptor-Interacting Protein antibodyAnti-Sstr-Interacting Protein antibodyAnti-Sstrip antibodyAnti-SHANK1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
