Anti-SH3BP2 antibody (392-561) (STJ112281)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal SH3BP2 (392-561) antibody for use in WB and ELISA in human and mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | SH3BP2 |
| Gene ID | 6452 |
| Uniprot ID | 3BP2_HUMAN |
| Immunogen Region | 392-561 |
| Immunogen Sequence | VPEAMARPAVLPRPEKPQLP HLQRSPPDGQSFRSFSFEKP RQPSQADTGGDDSDEDYEKV PLPNSVFVNTTESCEVERLF KATSPRGEPQDGLYCIRNSS TKSGKVLVVWDETSNKVRNY RIFEKDSKFYLEGEVLFVSV GSMVEHYHTHVLPSHQSLLL RHPYGYTGPR |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 392-561 of human SH3BP2 (NP_001116153.1). |
Additional Info
| Tissue Specificity | Expressed in a variety of tissues including lung, liver, skeletal muscle, kidney and pancreas. |
| Post Translational Modifications | Phosphorylated. Phosphorylation at Tyr-448 may stimulate the activity of the LYN kinase. |
| Function | Binds differentially to the SH3 domains of certain proteins of signal transduction pathways. Binds to phosphatidylinositols.linking the hemopoietic tyrosine kinase fes to the cytoplasmic membrane in a phosphorylation dependent mechanism. |
| Protein Name | Sh3 Domain-Binding Protein 23bp-2 |
| Database Links | |
| Cellular Localisation | |
| Alternative Antibody Names | Anti-Sh3 Domain-Binding Protein 2 antibodyAnti-3bp-2 antibodyAnti-SH3BP2 antibodyAnti-3BP2 antibodyAnti-RES4-23 antibody |
Information sourced from Uniprot.org