| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | SH3BP2 |
| Gene ID: | 6452 |
| Uniprot ID: | 3BP2_HUMAN |
| Immunogen Region: | 392-561 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 392-561 of human SH3BP2 (NP_001116153.1). |
| Immunogen Sequence: | VPEAMARPAVLPRPEKPQLP HLQRSPPDGQSFRSFSFEKP RQPSQADTGGDDSDEDYEKV PLPNSVFVNTTESCEVERLF KATSPRGEPQDGLYCIRNSS TKSGKVLVVWDETSNKVRNY RIFEKDSKFYLEGEVLFVSV GSMVEHYHTHVLPSHQSLLL RHPYGYTGPR |
| Tissue Specificity | Expressed in a variety of tissues including lung, liver, skeletal muscle, kidney and pancreas. |
| Post Translational Modifications | Phosphorylated. Phosphorylation at Tyr-448 may stimulate the activity of the LYN kinase. |
| Function | Binds differentially to the SH3 domains of certain proteins of signal transduction pathways. Binds to phosphatidylinositols.linking the hemopoietic tyrosine kinase fes to the cytoplasmic membrane in a phosphorylation dependent mechanism. |
| Protein Name | Sh3 Domain-Binding Protein 23bp-2 |
| Alternative Antibody Names | Anti-Sh3 Domain-Binding Protein 2 antibodyAnti-3bp-2 antibodyAnti-SH3BP2 antibodyAnti-3BP2 antibodyAnti-RES4-23 antibody |
Information sourced from Uniprot.org