Anti-SGIP1 antibody (427-477 aa) (STJ195008)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human SGIP1 at the amino acid range 427-477
General Information
| Short Description | Rabbit polyclonal anti-SH3-containing GRB2-like protein 3-interacting protein 1 (427-477 aa) for use in WB and IHC in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000IHC-P 1:50-300 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | SGIP1 |
| Gene ID | 84251 |
| Uniprot ID | SGIP1_HUMAN |
| Immunogen | Synthesized peptide derived from the human SGIP1 at the amino acid range 427-477 |
| Immunogen Region | 427-477 aa |
| Specificity | This antibody detects endogenous levels of SGIP1 at Human/Mouse/Rat |
Additional Info
| Function | May function in clathrin-mediated endocytosis. Has both a membrane binding/tubulating activity and the ability to recruit proteins essential to the formation of functional clathrin-coated pits. Has a preference for membranes enriched in phosphatidylserine and phosphoinositides and is required for the endocytosis of the transferrin receptor. May also bind tubulin. May play a role in the regulation of energy homeostasis. |
| Protein Name | Sh3-Containing Grb2-Like Protein 3-Interacting Protein 1Endophilin-3-Interacting Protein |
| Database Links | Reactome: R-HSA-8856825Reactome: R-HSA-8856828 |
| Cellular Localisation | MembraneClathrin-Coated PitPeripheral Membrane ProteinCytoplasmic Side |
| Alternative Antibody Names | Anti-Sh3-Containing Grb2-Like Protein 3-Interacting Protein 1 antibodyAnti-Endophilin-3-Interacting Protein antibodyAnti-SGIP1 antibody |
Information sourced from Uniprot.org