| Host: | Rabbit |
| Applications: | ELISA/IHC/IP/WB |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-SFRP5 (150-200) is suitable for use in ELISA, Immunohistochemistry, Immunoprecipitation and Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Biotin |
| Isotype: | IgG |
| Formulation: | Contains Tris, HCl/Glycine buffer pH 7.4-7.8, 30% Glycerol and 0.5% BSA, along with cryo-protective agents, Hepes, and long-term preservatives (0.02% Sodium Azide). |
| Purification: | Affinity Purified |
| Concentration: | 0.67 µg/µl |
| Dilution Range: | WB: 1:500DB: 1:10, 000ELISA: 1:10, 000IP: 1:200IHC: 1:50-1:150 |
| Storage Instruction: | Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
| Gene Symbol: | SFRP5 |
| Gene ID: | 6425 |
| Uniprot ID: | SFRP5_HUMAN |
| Immunogen Region: | 150-200 |
| Immunogen: | Synthetic peptide taken within amino acid region 150-200 on SFRP5 protein. |
| Tissue Specificity | Highly expressed in the retinal pigment epithelium (RPE) and pancreas. Weak expression in heart, liver and muscle. |
| Function | Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP5 may be involved in determining the polarity of photoreceptor, and perhaps, other cells in the retina. |
| Protein Name | Secreted Frizzled-Related Protein 5Sfrp-5Frizzled-Related Protein 1bFrp-1bSecreted Apoptosis-Related Protein 3Sarp-3 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Secreted Frizzled-Related Protein 5 antibodyAnti-Sfrp-5 antibodyAnti-Frizzled-Related Protein 1b antibodyAnti-Frp-1b antibodyAnti-Secreted Apoptosis-Related Protein 3 antibodyAnti-Sarp-3 antibodyAnti-SFRP5 antibodyAnti-FRP1B antibodyAnti-SARP3 antibody |
Information sourced from Uniprot.org