| Host: | Goat |
| Applications: | Pep-ELISA/WB/IHC |
| Reactivity: | Human/Mouse/Rat/Cow/Pig |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Goat polyclonal antibody anti-SFRP4 (Internal) is suitable for use in ELISA, Western Blot and Immunohistochemistry research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: | 0.5 mg/mL |
| Dilution Range: | Peptide ELISA: antibody detection limit dilution 1:32000.WB: Approx 40kDa band observed in Human Uterus lysates (calculated MW of 39.8kDa according to NP_003005.2). Recommended concentration: 1-3µg/ml.IHC: In paraffin embedded Human Uterus |
| Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: | SFRP4 |
| Gene ID: | 6424 |
| Uniprot ID: | SFRP4_HUMAN |
| Immunogen Region: | Internal |
| Accession Number: | NP_003005.2 |
| Immunogen Sequence: | TNSSCQCPHILPHQD |
| Function | Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP4 plays a role in bone morphogenesis. May also act as a regulator of adult uterine morphology and function. May also increase apoptosis during ovulation possibly through modulation of FZ1/FZ4/WNT4 signaling. Has phosphaturic effects by specifically inhibiting sodium-dependent phosphate uptake. |
| Protein Name | Secreted Frizzled-Related Protein 4Sfrp-4Frizzled Protein - Human EndometriumFrphe |
| Cellular Localisation | SecretedCytoplasmic In Ovarian Tumor Cells |
| Alternative Antibody Names | Anti-Secreted Frizzled-Related Protein 4 antibodyAnti-Sfrp-4 antibodyAnti-Frizzled Protein - Human Endometrium antibodyAnti-Frphe antibodyAnti-SFRP4 antibodyAnti-FRPHE antibody |
Information sourced from Uniprot.org