Anti-SFRP2 antibody (25-295) (STJ27336)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal SFRP2 (25-295) antibody for use in WB and ELISA in mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.09% Sodium Azide, 50% Glycerol, pH7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | SFRP2 |
| Gene ID | 6423 |
| Uniprot ID | SFRP2_HUMAN |
| Immunogen Region | 25-295 |
| Immunogen Sequence | LFLFGQPDFSYKRSNCKPIP ANLQLCHGIEYQNMRLPNLL GHETMKEVLEQAGAWIPLVM KQCHPDTKKFLCSLFAPVCL DDLDETIQPCHSLCVQVKDR CAPVMSAFGFPWPDMLECDR FPQDNDLCIPLASSDHLLPA TEEAPKVCEACKNKNDDDND IMETLCKNDFALKIKVKEIT YINRDTKIILETKSKTIYKL NGVSERDLKKSVLWLKDSLQ CTCEEMNDINAPYLVMGQK |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 25-295 of human SFRP2 (NP_003004.1). |
Additional Info
| Tissue Specificity | Expressed in adipose tissue, heart, brain, skeletal muscle, pancreas, thymus, prostate, testis, ovary, small intestine and colon. Highest levels in adipose tissue, small intestine and colon. |
| Function | Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP2 may be important for eye retinal development and for myogenesis. |
| Protein Name | Secreted Frizzled-Related Protein 2Frp-2Sfrp-2Secreted Apoptosis-Related Protein 1Sarp-1 |
| Database Links | Reactome: R-HSA-201681Reactome: R-HSA-3772470 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Secreted Frizzled-Related Protein 2 antibodyAnti-Frp-2 antibodyAnti-Sfrp-2 antibodyAnti-Secreted Apoptosis-Related Protein 1 antibodyAnti-Sarp-1 antibodyAnti-SFRP2 antibodyAnti-FRP2 antibodyAnti-SARP1 antibodyAnti-FKSG12 antibodyAnti-UNQ361 antibodyAnti-PRO697 antibody |
Information sourced from Uniprot.org