| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:1000 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | SFRP2 |
| Gene ID: | 6423 |
| Uniprot ID: | SFRP2_HUMAN |
| Immunogen Region: | 25-295 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 25-295 of human SFRP2 (NP_003004.1). |
| Immunogen Sequence: | LFLFGQPDFSYKRSNCKPIP ANLQLCHGIEYQNMRLPNLL GHETMKEVLEQAGAWIPLVM KQCHPDTKKFLCSLFAPVCL DDLDETIQPCHSLCVQVKDR CAPVMSAFGFPWPDMLECDR FPQDNDLCIPLASSDHLLPA TEEAPKVCEACKNKNDDDND IMETLCKNDFALKIKVKEIT YINRDTKIILETKSKTIYKL NGVSERDLKKSVLWLKDSLQ CTCEEMNDINAPYLVMGQK |
| Tissue Specificity | Expressed in adipose tissue, heart, brain, skeletal muscle, pancreas, thymus, prostate, testis, ovary, small intestine and colon. Highest levels in adipose tissue, small intestine and colon. |
| Function | Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP2 may be important for eye retinal development and for myogenesis. |
| Protein Name | Secreted Frizzled-Related Protein 2 Frp-2 Sfrp-2 Secreted Apoptosis-Related Protein 1 Sarp-1 |
| Database Links | Reactome: R-HSA-201681 Reactome: R-HSA-3772470 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Secreted Frizzled-Related Protein 2 antibody Anti-Frp-2 antibody Anti-Sfrp-2 antibody Anti-Secreted Apoptosis-Related Protein 1 antibody Anti-Sarp-1 antibody Anti-SFRP2 antibody Anti-FRP2 antibody Anti-SARP1 antibody Anti-FKSG12 antibody Anti-UNQ361 antibody Anti-PRO697 antibody |
Information sourced from Uniprot.org