| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | SERPINE2 |
| Gene ID: | 5270 |
| Uniprot ID: | GDN_HUMAN |
| Immunogen Region: | 20-398 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 20-398 of human SERPINE2 (NP_006207.1). |
| Immunogen Sequence: | SHFNPLSLEELGSNTGIQVF NQIVKSRPHDNIVISPHGIA SVLGMLQLGADGRTKKQLAM VMRYGVNGVGKILKKINKAI VSKKNKDIVTVANAVFVKNA SEIEVPFVTRNKDVFQCEVR NVNFEDPASACDSINAWVKN ETRDMIDNLLSPDLIDGVLT RLVLVNAVYFKGLWKSRFQP ENTKKRTFVAADGKSYQVPM LAQLSVFRCGSTSAPNDLWY NFIELPYHGESISMLIALP |
| Function | Serine protease inhibitor with activity toward thrombin, trypsin, and urokinase. Promotes neurite extension by inhibiting thrombin. Binds heparin. |
| Protein Name | Glia-Derived NexinGdnPeptidase Inhibitor 7Pi-7Protease Nexin 1Pn-1Protease Nexin ISerpin E2 |
| Database Links | Reactome: R-HSA-140837Reactome: R-HSA-140875Reactome: R-HSA-75205 |
| Cellular Localisation | SecretedExtracellular Space |
| Alternative Antibody Names | Anti-Glia-Derived Nexin antibodyAnti-Gdn antibodyAnti-Peptidase Inhibitor 7 antibodyAnti-Pi-7 antibodyAnti-Protease Nexin 1 antibodyAnti-Pn-1 antibodyAnti-Protease Nexin I antibodyAnti-Serpin E2 antibodyAnti-SERPINE2 antibodyAnti-PI7 antibodyAnti-PN1 antibody |
Information sourced from Uniprot.org
