Anti-SERPINB6 antibody (STJ191393)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from part of the human protein
General Information
| Short Description | Rabbit polyclonal anti-Serpin B6 for use in WB and ELISA in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | SERPINB6 |
| Gene ID | 5269 |
| Uniprot ID | SPB6_HUMAN |
| Immunogen | Synthesized peptide derived from part of the human protein |
| Specificity | SPB6 Polyclonal Antibody detects endogenous levels of protein. |
Additional Info
| Function | May be involved in the regulation of serine proteinases present in the brain or extravasated from the blood. Inhibitor of cathepsin G, kallikrein-8 and thrombin. May play an important role in the inner ear in the protection against leakage of lysosomal content during stress and loss of this protection results in cell death and sensorineural hearing loss. |
| Protein Name | Serpin B6Cytoplasmic AntiproteinaseCapPeptidase Inhibitor 6Pi-6Placental Thrombin Inhibitor |
| Database Links | Reactome: R-HSA-6798695Reactome: R-HSA-75205 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Serpin B6 antibodyAnti-Cytoplasmic Antiproteinase antibodyAnti-Cap antibodyAnti-Peptidase Inhibitor 6 antibodyAnti-Pi-6 antibodyAnti-Placental Thrombin Inhibitor antibodyAnti-SERPINB6 antibodyAnti-PI6 antibodyAnti-PTI antibody |
Information sourced from Uniprot.org