Anti-SERPINA10 antibody (165-444) (STJ29186)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal SERPINA10 (165-444) antibody for use in WB, IHC-P and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000IHC-P:1:50-1:100ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | SERPINA10 |
| Gene ID | 51156 |
| Uniprot ID | ZPI_HUMAN |
| Immunogen Region | 165-444 |
| Immunogen Sequence | FAFIHKDFDVKETFFNLSKR YFDTECVPMNFRNASQAKRL MNHYINKETRGKIPKLFDEI NPETKLILVDYILFKGKWLT PFDPVFTEVDTFHLDKYKTI KVPMMYGAGKFASTFDKNFR CHVLKLPYQGNATMLVVLME KMGDHLALEDYLTTDLVETW LRNMKTRNMEVFFPKFKLDQ KYEMHELLRQMGIRRIFSPF ADLSELSATGRNLQVSRVLQ RTVIEVDERGTEAVAGILS |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 165-444 of human SERPINA10 (NP_001094077.1). |
Additional Info
| Tissue Specificity | Expressed by the liver and secreted in plasma. |
| Post Translational Modifications | Phosphorylated by FAM20C in the extracellular medium. |
| Function | Inhibits activity of the coagulation protease factor Xa in the presence of PROZ, calcium and phospholipids. Also inhibits factor XIa in the absence of cofactors. |
| Protein Name | Protein Z-Dependent Protease InhibitorPz-Dependent Protease InhibitorPziSerpin A10 |
| Database Links | Reactome: R-HSA-381426Reactome: R-HSA-8957275 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Protein Z-Dependent Protease Inhibitor antibodyAnti-Pz-Dependent Protease Inhibitor antibodyAnti-Pzi antibodyAnti-Serpin A10 antibodyAnti-SERPINA10 antibodyAnti-ZPI antibodyAnti-UNQ707 antibodyAnti-PRO1358 antibody |
Information sourced from Uniprot.org