Host: |
Rabbit |
Applications: |
WB/IF/ICC/ELISA |
Reactivity: |
Human/Mouse/Rat |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
Purification: |
Affinity purification |
Concentration: |
Lot specific |
Dilution Range: |
WB:1:500-1:2000IF/ICC:1:20-1:100ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
SERPINA10 |
Gene ID: |
51156 |
Uniprot ID: |
ZPI_HUMAN |
Immunogen Region: |
165-444 |
Specificity: |
Recombinant fusion protein containing a sequence corresponding to amino acids 165-444 of human SERPINA10 (NP_001094077.1). |
Immunogen Sequence: |
FAFIHKDFDVKETFFNLSKR YFDTECVPMNFRNASQAKRL MNHYINKETRGKIPKLFDEI NPETKLILVDYILFKGKWLT PFDPVFTEVDTFHLDKYKTI KVPMMYGAGKFASTFDKNFR CHVLKLPYQGNATMLVVLME KMGDHLALEDYLTTDLVETW LRNMKTRNMEVFFPKFKLDQ KYEMHELLRQMGIRRIFSPF ADLSELSATGRNLQVSRVLQ RTVIEVDERGTEAVAGILS |
Tissue Specificity | Expressed by the liver and secreted in plasma. |
Post Translational Modifications | Phosphorylated by FAM20C in the extracellular medium. |
Function | Inhibits activity of the coagulation protease factor Xa in the presence of PROZ, calcium and phospholipids. Also inhibits factor XIa in the absence of cofactors. |
Protein Name | Protein Z-Dependent Protease InhibitorPz-Dependent Protease InhibitorPziSerpin A10 |
Database Links | Reactome: R-HSA-381426Reactome: R-HSA-8957275 |
Cellular Localisation | Secreted |
Alternative Antibody Names | Anti-Protein Z-Dependent Protease Inhibitor antibodyAnti-Pz-Dependent Protease Inhibitor antibodyAnti-Pzi antibodyAnti-Serpin A10 antibodyAnti-SERPINA10 antibodyAnti-ZPI antibodyAnti-UNQ707 antibodyAnti-PRO1358 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance