Anti-Serotonin Receptor 3B/HTR3B antibody (Internal) (STJ71971)

SKU:
STJ71971-100
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Host: Goat
Applications: Pep-ELISA/WB
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Goat polyclonal antibody anti-Serotonin Receptor 3B/HTR3B (Internal) is suitable for use in ELISA and Western Blot research applications.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA
Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration: 0.5 mg/mL
Dilution Range: Peptide ELISA: antibody detection limit dilution 1:16000.
WB: Approx 51kDa band observed in Human Brain (Cerebral Cortex, Hippocampus and Amygdala) lysates (calculated MW of 50.3kDa according to NP_006019.1). Recommended concentration: 1-3µg/ml.
Storage Instruction: Store at-20°C on receipt and minimise freeze-thaw cycles.
Gene Symbol: HTR3B
Gene ID: 9177
Uniprot ID: 5HT3B_HUMAN
Immunogen Region: Internal
Accession Number: NP_006019.1
Immunogen Sequence: SNYLQTQDQTDQQE
Post Translational Modifications N-glycosylation required for membrane localization.
Function Forms serotonin (5-hydroxytryptamine/5-HT3)-activated cation-selective channel complexes, which when activated cause fast, depolarizing responses in neurons.
Protein Name 5-Hydroxytryptamine Receptor 3b
5-Ht3-B
5-Ht3b
Serotonin Receptor 3b
Database Links Reactome: R-HSA-112314
Cellular Localisation Postsynaptic Cell Membrane
Multi-Pass Membrane Protein
Cell Membrane
Presumably Retained Within The Endoplasmic Reticulum Unless Complexed With Htr3a
Alternative Antibody Names Anti-5-Hydroxytryptamine Receptor 3b antibody
Anti-5-Ht3-B antibody
Anti-5-Ht3b antibody
Anti-Serotonin Receptor 3b antibody
Anti-HTR3B antibody

Information sourced from Uniprot.org