| Host: | Goat |
| Applications: | Pep-ELISA/FC/IHC/ICC |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Goat polyclonal antibody anti-Serotonin receptor 3A/HTR3A (Internal) is suitable for use in ELISA, Flow Cytometry, Immunohistochemistry and Immunocytochemistry research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: | 0.5 mg/mL |
| Dilution Range: | Peptide ELISA: antibody detection limit dilution 1:128000.IHC: Paraffin embedded Human Small Intestine. Recommended concentration: 3.75µg/ml. Immunocytochemistry:This product has been successfully used in ICC on Rat: Lu CL |
| Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: | HTR3A |
| Gene ID: | 3359 |
| Uniprot ID: | 5HT3A_HUMAN |
| Immunogen Region: | Internal |
| Accession Number: | NP_998786.3 NP_000860.3; NP_001155244.1 |
| Specificity: | This antibody is expected to recognise all three reported isoforms |
| Immunogen Sequence: | GPQDFEKSPRDR |
| Function | Forms serotonin (5-hydroxytryptamine/5-HT3)-activated cation-selective channel complexes, which when activated cause fast, depolarizing responses in neurons. |
| Protein Name | 5-Hydroxytryptamine Receptor 3a5-Ht3-A5-Ht3a5-Hydroxytryptamine Receptor 35-Ht-35-Ht3rSerotonin Receptor 3aSerotonin-Gated Ion Channel Receptor |
| Database Links | Reactome: R-HSA-112314 |
| Cellular Localisation | Postsynaptic Cell MembraneMulti-Pass Membrane ProteinCell Membrane |
| Alternative Antibody Names | Anti-5-Hydroxytryptamine Receptor 3a antibodyAnti-5-Ht3-A antibodyAnti-5-Ht3a antibodyAnti-5-Hydroxytryptamine Receptor 3 antibodyAnti-5-Ht-3 antibodyAnti-5-Ht3r antibodyAnti-Serotonin Receptor 3a antibodyAnti-Serotonin-Gated Ion Channel Receptor antibodyAnti-HTR3A antibodyAnti-5HT3R antibodyAnti-HTR3 antibody |
Information sourced from Uniprot.org