| Short Description : | Rabbit polyclonal anti-Septin-14 (341-390 aa) for use in WB and IHC in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/IHC |
| Host: | Rabbit |
| Reactivity: | Human/Rat/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | 1 mg/mL |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range: | WB 1:500-2000IHC-P 1:50-300 |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | SEPTIN14 |
| Gene ID: | 346288 |
| Uniprot ID: | SEP14_HUMAN |
| Immunogen: | The antiserum was produced against synthesized peptide derived from the human SEPT14 at the amino acid range 341-390 |
| Immunogen Region: | 341-390 aa |
| Specificity: | Septin 14 Polyclonal Antibody detects endogenous levels of Septin 14 protein. |
| Function | Filament-forming cytoskeletal GTPase (Probable). Involved in the migration of cortical neurons and the formation of neuron leading processes during embryonic development. Plays a role in sperm head formation during spermiogenesis, potentially via facilitating localization of ACTN4 to cell filaments. |
| Protein Name | Septin-14 |
| Database Links | |
| Cellular Localisation | CytoplasmCytoskeletonCell ProjectionAxonDendritePerikaryonPerinuclear RegionCytoplasmic VesicleSecretory VesicleAcrosomeColocalizes With Actin Stress FibersExpressed In The Perinuclear Rim And Manchette Structure In Early Elongating Spermatids During Spermiogenesis |
| Alternative Antibody Names | Anti-Septin-14 antibodyAnti-SEPTIN14 antibodyAnti-SEPT14 antibody |
Information sourced from Uniprot.org
