• Biotinylated STJ71734 (1ug/ml) staining of Human Testis lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence, using streptavidin-HRP and using NAP blocker as a substitute for skimmed milk.

Anti-SEPT6, Biotinylated antibody (Internal) {Biotin} (STJ73489)

SKU:
STJ73489-100

£303.50
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Host: Goat
Applications: Pep-ELISA/WB
Reactivity: Human/Cow/Dog
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Goat polyclonal antibody anti-SEPT6, Biotinylated (Internal) is suitable for use in ELISA and Western Blot research applications.
Clonality: Polyclonal
Conjugation: Biotin
Isotype: IgG
Formulation: 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA
Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration: 0.5 mg/mL
Dilution Range: WB-0.03-1µg/ml
ELISA-antibody detection limit dilution 1:4000.
Storage Instruction: Store at-20°C on receipt and minimise freeze-thaw cycles.
Gene Symbol: SEPTIN6
Gene ID: 23157
Uniprot ID: SEPT6_HUMAN
Immunogen Region: Internal
Accession Number: NP_665798.1; NP_055944.2; NP_665801.1
Specificity: This antibody is expected to recognize the reported isoforms NP_665798.1, NP_055944.2 and NP_665801.1. Reported variants NP_665799.1 and NP_665798.1 represent identical protein.
Immunogen Sequence: DEVNAFKQRKTA.
Function Filament-forming cytoskeletal GTPase. Required for normal organization of the actin cytoskeleton. Involved in cytokinesis. May play a role in HCV RNA replication. Forms a filamentous structure with SEPTIN12, SEPTIN6, SEPTIN2 and probably SEPTIN4 at the sperm annulus which is required for the structural integrity and motility of the sperm tail during postmeiotic differentiation.
Protein Name Septin-6
Cellular Localisation Cytoplasm
Cytoskeleton
Spindle
Chromosome
Centromere
Kinetochore
Cleavage Furrow
Midbody
Cell Projection
Cilium
Flagellum
In Metaphase Cells
Localized Within The Microtubule Spindle
At The Metaphase Plate
In Close Apposition To The Kinetochores Of The Congressed Chromosomes
In Cells Undergoing Cytokinesis
Localized To The Midbody
The Ingressing Cleavage Furrow
And The Central Spindle
Found In The Sperm Annulus
Alternative Antibody Names Anti-Septin-6 antibody
Anti-SEPTIN6 antibody
Anti-KIAA0128 antibody
Anti-SEP2 antibody
Anti-SEPT6 antibody

Information sourced from Uniprot.org

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