| Function | Plays an important role in integrin-mediated signaling and functions both in regulating cell migration and immune responses. Promotes formation of focal adhesion complexes, activation of the protein kinase PTK2/FAK1 and subsequent phosphorylation of MAPK1 and MAPK3. Promotes production of pro-inflammatory cytokines by monocytes and macrophages. Plays an important role in modulating inflammation and T-cell-mediated immune responses. Promotes axon growth in the embryonic olfactory bulb. Promotes attachment, spreading and dendrite outgrowth in melanocytes. |
| Protein Name | Semaphorin-7aCdw108Jmh Blood Group AntigenJohn-Milton-Hargen Human Blood Group AgSemaphorin-K1Sema K1Semaphorin-LSema LCd Antigen Cd108 |
| Database Links | Reactome: R-HSA-416700 |
| Cellular Localisation | Cell MembraneLipid-AnchorGpi-AnchorExtracellular SideDetected In A Punctate Pattern On The Cell Membrane Of Basal And Supra-Basal Skin Keratinocytes |
| Alternative Antibody Names | Anti-Semaphorin-7a antibodyAnti-Cdw108 antibodyAnti-Jmh Blood Group Antigen antibodyAnti-John-Milton-Hargen Human Blood Group Ag antibodyAnti-Semaphorin-K1 antibodyAnti-Sema K1 antibodyAnti-Semaphorin-L antibodyAnti-Sema L antibodyAnti-Cd Antigen Cd108 antibodyAnti-SEMA7A antibodyAnti-CD108 antibodyAnti-SEMAL antibody |
Information sourced from Uniprot.org
