Host: | Rabbit |
Applications: | WB/IF/ICC/ELISA |
Reactivity: | Human/Mouse/Rat |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Clonality : | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
Purification: | Affinity purification |
Concentration: | Lot specific |
Dilution Range: | WB:1:500-1:1000IF/ICC:1:100-1:500ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | SELENOP |
Gene ID: | 6414 |
Uniprot ID: | SEPP1_HUMAN |
Immunogen Region: | 60-200 |
Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 60-200 of human SELENOP (NP_001078955.1). |
Immunogen Sequence: | YLCILQASKLEDLRVKLKKE GYSNISYIVVNHQGISSRLK YTHLKNKVSEHIPVYQQEEN QTDVWTLLNGSKDDFLIYDR CGRLVYHLGLPFSFLTFPYV EEAIKIAYCEKKCGNCSLTT LKDEDFCKRVSLATVDKTVE T |
Tissue Specificity | Made in the liver and heart and secreted into the plasma. It is also found in the kidney. |
Post Translational Modifications | Phosphorylation sites are present in the extracellular medium. |
Function | Might be responsible for some of the extracellular antioxidant defense properties of selenium or might be involved in the transport of selenium. May supply selenium to tissues such as brain and testis. |
Protein Name | Selenoprotein PSep |
Database Links | Reactome: R-HSA-114608 |
Cellular Localisation | SecretedPasses From Plasma Into The Glomerular Filtrate Where It Is Removed By Endocytosis Mediated By Lrp2 In The Proximal Tubule Epithelium |
Alternative Antibody Names | Anti-Selenoprotein P antibodyAnti-Sep antibodyAnti-SELENOP antibodyAnti-SELP antibodyAnti-SEPP1 antibody |
Information sourced from Uniprot.org