| Host: |
Rabbit |
| Applications: |
WB/IHC-P/IF/ICC/ELISA |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality: |
Monoclonal |
| Clone ID: |
SRM |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.09% Sodium Azide, 0.05% BSA, 50% Glycerol, pH 7.3. |
| Purification: |
Affinity purification |
| Concentration: |
Lot specific |
| Dilution Range: |
WB:1:5000-1:30000IHC-P:1:4000-1:40000IF/ICC:1:3200-1:12800ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Gene Symbol: |
CAVIN2 |
| Gene ID: |
8436 |
| Uniprot ID: |
CAVN2_HUMAN |
| Immunogen Region: |
326-425 aa |
| Specificity: |
A synthetic peptide corresponding to a sequence within amino acids 326-425 of human SDPR/Cavin-2 (NP_004648.1). |
| Immunogen Sequence: |
EDLPSSEQMPNDQEEESFAE GHSEASLASALVEGEIAEEA AEKATSRGSNSGMDSNIDLT IVEDEEEESVALEQAQKVRY EGSYALTSEEAERSDGDPVQ PAVLQVHQTS |
| Tissue Specificity | Highly expressed in heart and lung, and expressed at lower levels in brain, kidney, liver, pancreas, placenta, and skeletal muscle. |
| Post Translational Modifications | Phosphorylated on Ser residues. |
| Function | Plays an important role in caveolar biogenesis and morphology. Regulates caveolae morphology by inducing membrane curvature within caveolae. Plays a role in caveola formation in a tissue-specific manner. Required for the formation of caveolae in the lung and fat endothelia but not in the heart endothelia. Negatively regulates the size or stability of CAVIN complexes in the lung endothelial cells. May play a role in targeting PRKCA to caveolae. |
| Protein Name | Caveolae-Associated Protein 2Cavin-2Ps-P68Phosphatidylserine-Binding ProteinSerum Deprivation-Response Protein |
| Cellular Localisation | CytoplasmCytosolMembraneCaveolaLocalizes In The Caveolae In A Caveolin-Dependent Manner |
| Alternative Antibody Names | Anti-Caveolae-Associated Protein 2 antibodyAnti-Cavin-2 antibodyAnti-Ps-P68 antibodyAnti-Phosphatidylserine-Binding Protein antibodyAnti-Serum Deprivation-Response Protein antibodyAnti-CAVIN2 antibodyAnti-SDPR antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
