Anti-SCNN1D antibody (411-460 aa) (STJ92917)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from the human SCNN1D at the amino acid range 411-460
General Information
| Short Description | Rabbit polyclonal anti-Amiloride-sensitive sodium channel subunit delta channel subunit delta (411-460 aa) for use in WB, IF and ELISA in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IF/ELISA |
| Host | Rabbit |
| Reactivity | Human/Rat/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-1:2000IF 1:200-1:1000ELISA 1:20000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | SCNN1D |
| Gene ID | 6339 |
| Uniprot ID | SCNND_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from the human SCNN1D at the amino acid range 411-460 |
| Immunogen Region | 411-460 aa |
| Specificity | ENaC Delta Polyclonal Antibody detects endogenous levels of ENaC Delta protein. |
Additional Info
| Function | Potential alternative pore-forming subunit of the epithelial sodium channel (ENaC), capable of replacing the alpha/SCNN1A subunit, creating a more active channel with distinct properties. ENaC functions in epithelial tissues, where it facilitates the electrodiffusion of sodium ions from the extracellular fluid through the apical membrane of cells, with water following osmotically, regulating sodium balance and fluid homeostasis. This subunit could also function independently as a sodium channel or assemble into other tissue-specific heterotrimeric sodium channels. Isoform 2: ENaC channels including this isoform exhibit greater conductance. |
| Protein Name | Epithelial Sodium Channel Subunit DeltaDelta-EnacEnacdEpithelial Na(+ Channel Subunit DeltaAmiloride-Sensitive Sodium Channel Subunit DeltaDelta-NachNonvoltage-Gated Sodium Channel 1 Subunit DeltaScned |
| Database Links | Reactome: R-HSA-2672351Reactome: R-HSA-9730628 |
| Cellular Localisation | Apical Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Epithelial Sodium Channel Subunit Delta antibodyAnti-Delta-Enac antibodyAnti-Enacd antibodyAnti-Epithelial Na(+ Channel Subunit Delta antibodyAnti-Amiloride-Sensitive Sodium Channel Subunit Delta antibodyAnti-Delta-Nach antibodyAnti-Nonvoltage-Gated Sodium Channel 1 Subunit Delta antibodyAnti-Scned antibodyAnti-SCNN1D antibodyAnti-DNACH antibody |
Information sourced from Uniprot.org