Anti-SCG5 antibody (90-170 aa) (STJ191062)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human protein at the amino acid range 90-170
General Information
| Short Description | Rabbit polyclonal anti-Neuroendocrine protein 7B2 (90-170 aa) for use in WB and ELISA in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | SCG5 |
| Gene ID | 6447 |
| Uniprot ID | 7B2_HUMAN |
| Immunogen | Synthesized peptide derived from the human protein at the amino acid range 90-170 |
| Immunogen Region | 90-170 aa |
| Specificity | 7B2 Polyclonal Antibody detects endogenous levels of protein. |
Additional Info
| Function | Acts as a molecular chaperone for PCSK2/PC2, preventing its premature activation in the regulated secretory pathway. Binds to inactive PCSK2 in the endoplasmic reticulum and facilitates its transport from there to later compartments of the secretory pathway where it is proteolytically matured and activated. Also required for cleavage of PCSK2 but does not appear to be involved in its folding. Plays a role in regulating pituitary hormone secretion. The C-terminal peptide inhibits PCSK2 in vitro. |
| Protein Name | Neuroendocrine Protein 7b2Pituitary PolypeptideSecretogranin VSecretogranin-5Secretory Granule Endocrine Protein I Cleaved Into - N-Terminal Peptide - C-Terminal Peptide |
| Database Links | |
| Cellular Localisation | SecretedNeuroendocrine And Endocrine Secretory Granules |
| Alternative Antibody Names | Anti-Neuroendocrine Protein 7b2 antibodyAnti-Pituitary Polypeptide antibodyAnti-Secretogranin V antibodyAnti-Secretogranin-5 antibodyAnti-Secretory Granule Endocrine Protein I Cleaved Into - N-Terminal Peptide - C-Terminal Peptide antibodyAnti-SCG5 antibodyAnti-SGNE1 antibody |
Information sourced from Uniprot.org