Host: |
Rabbit |
Applications: |
WB/IHC/IF/ELISA |
Reactivity: |
Human/Rat |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-Secretogranin-3 (21-70 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: |
1 mg/mL |
Dilution Range: |
WB 1:500-1:2000IHC-P 1:100-300ELISA 1:20000IF 1:50-200 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
SCG3 |
Gene ID: |
29106 |
Uniprot ID: |
SCG3_HUMAN |
Immunogen Region: |
21-70 aa |
Specificity: |
Sg III Polyclonal Antibody detects endogenous levels of Sg III protein. |
Immunogen: |
The antiserum was produced against synthesized peptide derived from the N-terminal region of human SCG3 at the amino acid range 21-70 |
Post Translational Modifications | O-glycosylated. |
Function | Member of the granin protein family that regulates the biogenesis of secretory granules. Acts as a sorting receptor for intragranular proteins including chromogranin A/CHGA. May also play a role in angiogenesis. Promotes endothelial proliferation, migration and tube formation through MEK/ERK signaling pathway. |
Protein Name | Secretogranin-3Secretogranin IiiSgiii |
Database Links | Reactome: R-HSA-114608Reactome: R-HSA-381426Reactome: R-HSA-8957275 |
Cellular Localisation | Cytoplasmic VesicleSecretory VesicleSecretory Vesicle MembranePeripheral Membrane ProteinSecretedAssociated With The Secretory Granule Membrane Through Direct Binding To Cholesterol-Enriched Lipid Rafts |
Alternative Antibody Names | Anti-Secretogranin-3 antibodyAnti-Secretogranin Iii antibodyAnti-Sgiii antibodyAnti-SCG3 antibodyAnti-UNQ2502 antibodyAnti-PRO5990 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance