| Host: | Rabbit |
| Applications: | IHC/WB |
| Reactivity: | Mouse/Rat/Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-SCAMP5 (180-230 aa) is suitable for use in Immunohistochemistry and Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Lyophilised |
| Purification: | IgG purified |
| Dilution Range: | IHC, WB. A concentration of 10-50 µg/ml is recommended. The optimal concentration should be determined by the end user. Not tested in other applications. |
| Storage Instruction: | Maintain the lyophilised/reconstituted antibodies frozen at-20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, Glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles. |
| Gene Symbol: | Scamp5 |
| Gene ID: | 56807 |
| Uniprot ID: | SCAM5_MOUSE |
| Immunogen Region: | 180-230 aa |
| Specificity: | Specific for SCAMP5. |
| Immunogen: | A synthetic peptide from aa region 180-230 of rat SCAMP5 conjugated to blue carrier protein was used as the antigen. The peptide is homologous in mouse and shares 95% identity with human NA s. |
| Function | Required for the calcium-dependent exocytosis of signal sequence-containing cytokines such as CCL5. Probably acts in cooperation with the SNARE machinery. |
| Protein Name | Secretory Carrier-Associated Membrane Protein 5Secretory Carrier Membrane Protein 5 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinGolgi Apparatus MembraneGolgi ApparatusTrans-Golgi Network MembraneRecycling Endosome MembraneCytoplasmic VesicleSecretory VesicleSynaptic Vesicle MembraneMainly Localizes In Golgi Apparatus MembraneUpon Calcium-Triggered ExocytosisIt Translocates To The Cell MembraneHighly Enriched In Synaptic Vesicles |
| Alternative Antibody Names | Anti-Secretory Carrier-Associated Membrane Protein 5 antibodyAnti-Secretory Carrier Membrane Protein 5 antibodyAnti-Scamp5 antibody |
Information sourced from Uniprot.org