| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Histone deacetylase complex subunit SAP30 (140-220 aa) is suitable for use in Western Blot and ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000ELISA 1:5000-20000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | SAP30 |
| Gene ID: | 8819 |
| Uniprot ID: | SAP30_HUMAN |
| Immunogen Region: | 140-220 aa |
| Specificity: | SAP30 Polyclonal Antibody detects endogenous levels of protein. |
| Immunogen: | Synthesized peptide derived from the human protein at the amino acid range 140-220 |
| Function | Involved in the functional recruitment of the Sin3-histone deacetylase complex (HDAC) to a specific subset of N-CoR corepressor complexes. Capable of transcription repression by N-CoR. Active in deacetylating core histone octamers (when in a complex) but inactive in deacetylating nucleosomal histones. (Microbial infection) Involved in transcriptional repression of HHV-1 genes TK and gC. |
| Protein Name | Histone Deacetylase Complex Subunit Sap3030 Kda Sin3-Associated PolypeptideSin3 Corepressor Complex Subunit Sap30Sin3-Associated Polypeptide P30 |
| Database Links | Reactome: R-HSA-3214815Reactome: R-HSA-427413Reactome: R-HSA-9679191 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Histone Deacetylase Complex Subunit Sap30 antibodyAnti-30 Kda Sin3-Associated Polypeptide antibodyAnti-Sin3 Corepressor Complex Subunit Sap30 antibodyAnti-Sin3-Associated Polypeptide P30 antibodyAnti-SAP30 antibody |
Information sourced from Uniprot.org