| Host: | Rabbit |
| Applications: | WB |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Sterile alpha motif domain-containing protein 7 (341-391 aa) is suitable for use in Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:1000-2000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | SAMD7 |
| Gene ID: | 344658 |
| Uniprot ID: | SAMD7_HUMAN |
| Immunogen Region: | 341-391 aa |
| Specificity: | This antibody detects endogenous levels of human SAMD7 |
| Immunogen: | Synthesized peptide derived from the human SAMD7 at the amino acid range 341-391 |
| Function | Component of a Polycomb group (PcG) multiprotein PRC1-like complex, essential for establishing rod photoreceptor cell identity and function by silencing nonrod gene expression in developing rod photoreceptor cells. Via its association with the PRC1-like complex, promotes epigenetic repressive marks H3K27me3 and H2AK119ub marks in nonrod genes, silencing their transcription. Represses Crx-controlled photoreceptor-specific gene expression. |
| Protein Name | Sterile Alpha Motif Domain-Containing Protein 7Sam Domain-Containing Protein 7 |
| Database Links | |
| Cellular Localisation | NucleusCytoplasmCo-Localizes With Phc2 And Rnf2 In Nuclear Polycomb Bodies |
| Alternative Antibody Names | Anti-Sterile Alpha Motif Domain-Containing Protein 7 antibodyAnti-Sam Domain-Containing Protein 7 antibodyAnti-SAMD7 antibody |
Information sourced from Uniprot.org
