| Short Description : | Rabbit polyclonal anti-Retinoic acid receptor RXR-gamma (171-220 aa) for use in WB, IHC, IF and ELISA in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/IHC/IF/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | 1 mg/mL |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range: | WB 1:500-1:2000IHC 1:100-1:300IF 1:200-1:1000ELISA 1:10000 |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | RXRG |
| Gene ID: | 6258 |
| Uniprot ID: | RXRG_HUMAN |
| Immunogen: | The antiserum was produced against synthesized peptide derived from the human Retinoid X Receptor gamma at the amino acid range 171-220 |
| Immunogen Region: | 171-220 aa |
| Specificity: | RXR Gamma Polyclonal Antibody detects endogenous levels of RXR Gamma protein. |
| Post Translational Modifications | Acetylated by EP300. |
| Function | Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The RAR/RXR heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5. The high affinity ligand for RXRs is 9-cis retinoic acid. |
| Protein Name | Retinoic Acid Receptor Rxr-GammaNuclear Receptor Subfamily 2 Group B Member 3Retinoid X Receptor Gamma |
| Database Links | Reactome: R-HSA-383280Reactome: R-HSA-5362517 |
| Cellular Localisation | NucleusCytoplasm |
| Alternative Antibody Names | Anti-Retinoic Acid Receptor Rxr-Gamma antibodyAnti-Nuclear Receptor Subfamily 2 Group B Member 3 antibodyAnti-Retinoid X Receptor Gamma antibodyAnti-RXRG antibodyAnti-NR2B3 antibody |
Information sourced from Uniprot.org
