| Applications: | WB/IP/ChIP/ELISA |
| Host: | Rabbit |
| Reactivity: | Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Monoclonal |
| Clone ID : | SRM14838 |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Purification: | Affinity purification |
| Dilution Range: | WB, 1:1000-1:2000IP, 0.5 Mu g-4 Mu g antibody for 400 Mu g-600 Mu g extracts of whole cellsChIP, 3 Mu g antibody for 10 Mu g-15 Mu g of ChromatinELISA, Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | RXRB |
| Gene ID: | 6257 |
| Uniprot ID: | RXRB_HUMAN |
| Immunogen: | Synthetic peptide. This information is considered to be commercially sensitive. |
| Tissue Specificity | Expressed in aortic endothelial cells (at protein level). Expressed in monocytes. Expressed in a variety of tumor cell lines. |
| Function | Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The RAR/RXR heterodimers bind to the retinoic acid response elements (RARE). |
| Protein Name | Retinoic Acid Receptor Rxr-BetaNuclear Receptor Subfamily 2 Group B Member 2Retinoid X Receptor Beta |
| Database Links | Reactome: R-HSA-1989781Reactome: R-HSA-383280Reactome: R-HSA-5362517Reactome: R-HSA-9029558Reactome: R-HSA-9029569Reactome: R-HSA-9031525Reactome: R-HSA-9031528Reactome: R-HSA-9623433Reactome: R-HSA-9632974 |
| Cellular Localisation | NucleusCytoplasm |
| Alternative Antibody Names | Anti-Retinoic Acid Receptor Rxr-Beta antibodyAnti-Nuclear Receptor Subfamily 2 Group B Member 2 antibodyAnti-Retinoid X Receptor Beta antibodyAnti-RXRB antibodyAnti-NR2B2 antibody |
Information sourced from Uniprot.org
