| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Rat/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Relaxin receptor 1 (240-320 aa) is suitable for use in Western Blot and ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000ELISA 1:5000-20000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | RXFP1 |
| Gene ID: | 59350 |
| Uniprot ID: | RXFP1_HUMAN |
| Immunogen Region: | 240-320 aa |
| Specificity: | RXFP1 Polyclonal Antibody detects endogenous levels of protein. |
| Immunogen: | Synthesized peptide derived from the human protein at the amino acid range 240-320 |
| Function | Receptor for relaxins. The activity of this receptor is mediated by G proteins leading to stimulation of adenylate cyclase and an increase of cAMP. Binding of the ligand may also activate a tyrosine kinase pathway that inhibits the activity of a phosphodiesterase that degrades cAMP. |
| Protein Name | Relaxin Receptor 1Leucine-Rich Repeat-Containing G-Protein Coupled Receptor 7Relaxin Family Peptide Receptor 1 |
| Database Links | Reactome: R-HSA-418555Reactome: R-HSA-444821 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Relaxin Receptor 1 antibodyAnti-Leucine-Rich Repeat-Containing G-Protein Coupled Receptor 7 antibodyAnti-Relaxin Family Peptide Receptor 1 antibodyAnti-RXFP1 antibodyAnti-LGR7 antibody |
Information sourced from Uniprot.org