| Function | NAD(P)H oxidoreductase involved in the ubiquinone biosynthetic pathway. Required for the O-methyltransferase activity of COQ3. Able to catalyze the oxidoreduction of 3-demethylubiquinone into 3-demethylubiquinol in vitro. However, it is unclear if 3-demethylubiquinone constitutes a substrate in vivo. May also play a role in the regulation of retinal ganglion cell (RGC) neurite outgrowth, and hence in the development of the inner retina and optic nerve. Appears to be a potent inhibitor of regeneration following spinal cord injury. |
| Protein Name | Nad(Ph Oxidoreductase Rtn4ip1 - MitochondrialNogo-Interacting Mitochondrial ProteinReticulon-4-Interacting Protein 1 |
| Database Links | |
| Cellular Localisation | Mitochondrion MatrixMitochondrion Outer MembraneMainly Localizes To The Mitochondrial MatrixAlso Colocalizes With The Endoplasmic Reticulum Hspa5 At Spots Corresponding To Contacts With Mitochondria |
| Alternative Antibody Names | Anti-Nad(Ph Oxidoreductase Rtn4ip1 - Mitochondrial antibodyAnti-Nogo-Interacting Mitochondrial Protein antibodyAnti-Reticulon-4-Interacting Protein 1 antibodyAnti-RTN4IP1 antibodyAnti-NIMP antibody |
Information sourced from Uniprot.org
