Anti-RTF2 antibody (STJA0007925)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human RTF2
General Information
| Short Description | Rabbit polyclonal anti-Replication termination factor 2 for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | RTF2 |
| Gene ID | 51507 |
| Uniprot ID | RTF2_HUMAN |
| Immunogen | Synthesized peptide derived from human RTF2 |
| Specificity | This antibody detects endogenous levels of RTF2 at Human, Mouse, Rat |
Additional Info
| Function | Replication termination factor which is a component of the elongating replisome (Probable). Required for ATR pathway signaling upon DNA damage and has a positive activity during DNA replication. Might function to facilitate fork pausing at replication fork barriers like the rDNA. May be globally required to stimulate ATR signaling after the fork stalls or encounters a lesion (Probable). Interacts with nascent DNA. |
| Protein Name | Replication Termination Factor 2Rtf2Replication Termination Factor 2 Domain-Containing Protein 1 |
| Database Links | |
| Cellular Localisation | ChromosomeLocalizes At The Replication Fork |
| Alternative Antibody Names | Anti-Replication Termination Factor 2 antibodyAnti-Rtf2 antibodyAnti-Replication Termination Factor 2 Domain-Containing Protein 1 antibodyAnti-RTF2 antibodyAnti-C20orf43 antibodyAnti-RTFDC1 antibodyAnti-AD-007 antibodyAnti-CDA05 antibodyAnti-HSPC164 antibodyAnti-HSPC169 antibody |
Information sourced from Uniprot.org