• Formalin-fixed and paraffin-embedded human head and neck small cell carcinoma stained with anti-RRM1 antibody using peroxidase-conjugate and DAB chromogen. Note the cytoplasmic staining of tumor cells

Anti-RRM1 antibody (700-800aa) [ZR114] (STJ180594)

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STJ180594

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Host: Rabbit
Applications: IHC-P
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit monoclonal antibody anti-RRM1 (700-800aa) is suitable for use in Immunohistochemistry research applications.
Clonality: Monoclonal
Clone ID: ZR114
Conjugation: Unconjugated
Isotype: IgG
Formulation: Tris-HCI buffer containing stabilizing protein (BSA) and <0.1% ProClin
Purification: Affinity purified
Dilution Range: 1:100-200
Storage Instruction: Store at 2‐8°C for up to 24 months. Predilute: Ready to use, no reconstitution necessary. Concentrate: Use dilution range and appropriate lab‐standardized diluent. Stability after dilution: 7 days at 24°C, 3 months at 2‐8°C, 6months at ‐20°C.
Gene Symbol: RRM1
Gene ID: 6240
Uniprot ID: RIR1_HUMAN
Immunogen Region: 700-800aa
Specificity: Positive Control: Breast or colon carcinoma
Immunogen: Synthetic peptide corresponding to residues within aa700-800 of human RRM1
Function Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
Protein Name Ribonucleoside-Diphosphate Reductase Large Subunit
Ribonucleoside-Diphosphate Reductase Subunit M1
Ribonucleotide Reductase Large Subunit
Database Links Reactome: R-HSA-499943
Cellular Localisation Cytoplasm
Alternative Antibody Names Anti-Ribonucleoside-Diphosphate Reductase Large Subunit antibody
Anti-Ribonucleoside-Diphosphate Reductase Subunit M1 antibody
Anti-Ribonucleotide Reductase Large Subunit antibody
Anti-RRM1 antibody
Anti-RR1 antibody

Information sourced from Uniprot.org

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