| Host: | Rabbit |
| Applications: | IHC-P |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit monoclonal antibody anti-RRM1 (700-800aa) is suitable for use in Immunohistochemistry research applications. |
| Clonality : | Monoclonal |
| Clone ID : | ZR114 |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Tris-HCI buffer containing stabilizing protein (BSA) and <0.1% ProClin |
| Purification: | Affinity purified |
| Dilution Range: | 1:100-200 |
| Storage Instruction: | Store at 2‐8°C for up to 24 months. Predilute: Ready to use, no reconstitution necessary. Concentrate: Use dilution range and appropriate lab‐standardized diluent. Stability after dilution: 7 days at 24°C, 3 months at 2‐8°C, 6months at ‐20°C. |
| Gene Symbol: | RRM1 |
| Gene ID: | 6240 |
| Uniprot ID: | RIR1_HUMAN |
| Immunogen Region: | 700-800aa |
| Specificity: | Positive Control: Breast or colon carcinoma |
| Immunogen: | Synthetic peptide corresponding to residues within aa700-800 of human RRM1 |
| Function | Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. |
| Protein Name | Ribonucleoside-Diphosphate Reductase Large SubunitRibonucleoside-Diphosphate Reductase Subunit M1Ribonucleotide Reductase Large Subunit |
| Database Links | Reactome: R-HSA-499943 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Ribonucleoside-Diphosphate Reductase Large Subunit antibodyAnti-Ribonucleoside-Diphosphate Reductase Subunit M1 antibodyAnti-Ribonucleotide Reductase Large Subunit antibodyAnti-RRM1 antibodyAnti-RR1 antibody |
Information sourced from Uniprot.org