• Western blot analysis of lysates from HeLa and HepG2/MCF-7 cells, using RAD Antibody. The lane on the right is blocked with the synthesized peptide.
  • Immunofluorescence analysis of A549 cells, using RAD Antibody. The picture on the right is blocked with the synthesized peptide.
  • Immunohistochemistry analysis of paraffin-embedded human heart tissue, using RAD Antibody. The picture on the right is blocked with the synthesized peptide.
  • Western blot analysis of various cells using Rad GTPase Polyclonal Antibody

Anti-RRAD antibody (41-90 aa) (STJ95321)

SKU:
STJ95321

£46.00 - £226.00
Current Stock:
Host: Rabbit
Applications: WB/IHC/IF/ELISA
Reactivity: Human/Rat/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-GTP-binding protein RAD (41-90 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
IHC 1:100-1:300
IF 1:200-1:1000
ELISA 1:20000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: RRAD
Gene ID: 6236
Uniprot ID: RAD_HUMAN
Immunogen Region: 41-90 aa
Specificity: Rad GTPase Polyclonal Antibody detects endogenous levels of Rad GTPase protein.
Immunogen: The antiserum was produced against synthesized peptide derived from the human RAD at the amino acid range 41-90
Function May regulate basal voltage-dependent L-type Ca(2+) currents and be required for beta-adrenergic augmentation of Ca(2+) influx in cardiomyocytes, thereby regulating increases in heart rate and contractile force. May play an important role in cardiac antiarrhythmia via the strong suppression of voltage-gated L-type Ca(2+) currents. Regulates voltage-dependent L-type calcium channel subunit alpha-1C trafficking to the cell membrane. Inhibits cardiac hypertrophy through the calmodulin-dependent kinase II (CaMKII) pathway. Inhibits phosphorylation and activation of CAMK2D.
Protein Name Gtp-Binding Protein Rad
Rad1
Ras Associated With Diabetes
Database Links Reactome: R-HSA-9031628
Cellular Localisation Cell Membrane
Alternative Antibody Names Anti-Gtp-Binding Protein Rad antibody
Anti-Rad1 antibody
Anti-Ras Associated With Diabetes antibody
Anti-RRAD antibody
Anti-RAD antibody

Information sourced from Uniprot.org

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