| Function | Catalyzes uridine to pseudouridine isomerization (pseudouridylation) of specific mitochondrial mRNAs (mt-mRNAs), a post-transcriptional modification necessary for their translation. Acts at position 390 in COXI mt-mRNA and at position 697-699 in mitochondrial COXIII mt-mRNA. As a component of a functional protein-RNA module, consisting of RCC1L, NGRN, RPUSD3, RPUSD4, TRUB2, FASTKD2 and 16S mitochondrial ribosomal RNA (16S mt-rRNA), controls 16S mt-rRNA abundance and may play a role in mitochondrial ribosome biogenesis. |
| Protein Name | Mitochondrial Mrna Pseudouridine Synthase Rpusd3Rna Pseudouridylate Synthase Domain-Containing Protein 3 |
| Cellular Localisation | Mitochondrion MatrixLocalizes To Mitochondrial Rna GranulesPlatforms For Post-Transcriptional Rna Modification And Ribosome Assembly |
| Alternative Antibody Names | Anti-Mitochondrial Mrna Pseudouridine Synthase Rpusd3 antibodyAnti-Rna Pseudouridylate Synthase Domain-Containing Protein 3 antibodyAnti-RPUSD3 antibody |
Information sourced from Uniprot.org
