Anti-RPA4 antibody (STJ193094)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from part of the human protein
General Information
| Short Description | Rabbit polyclonal anti-Replication protein A 30 kDa subunit for use in WB and ELISA in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Rat/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | RPA4 |
| Gene ID | 29935 |
| Uniprot ID | RFA4_HUMAN |
| Immunogen | Synthesized peptide derived from part of the human protein |
| Specificity | RFA4 Polyclonal Antibody detects endogenous levels of protein. |
Additional Info
| Function | As part of the alternative replication protein A complex, aRPA, binds single-stranded DNA and probably plays a role in DNA repair. Compared to the RPA2-containing, canonical RPA complex, may not support chromosomal DNA replication and cell cycle progression through S-phase. The aRPA may not promote efficient priming by DNA polymerase alpha but could support DNA polymerase delta synthesis in the presence of PCNA and replication factor C (RFC), the dual incision/excision reaction of nucleotide excision repair and RAD51-dependent strand exchange. |
| Protein Name | Replication Protein A 30 Kda SubunitRp-A P30Replication Factor A Protein 4Rf-A Protein 4 |
| Database Links | Reactome: R-HSA-68962 |
| Cellular Localisation | NucleusLocalizes To Dna Repair Foci After Dna Damage |
| Alternative Antibody Names | Anti-Replication Protein A 30 Kda Subunit antibodyAnti-Rp-A P30 antibodyAnti-Replication Factor A Protein 4 antibodyAnti-Rf-A Protein 4 antibodyAnti-RPA4 antibody |
Information sourced from Uniprot.org