| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Rat/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Replication protein A 30 kDa subunit is suitable for use in Western Blot and ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000ELISA 1:5000-20000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | RPA4 |
| Gene ID: | 29935 |
| Uniprot ID: | RFA4_HUMAN |
| Specificity: | RFA4 Polyclonal Antibody detects endogenous levels of protein. |
| Immunogen: | Synthesized peptide derived from part of the human protein |
| Function | As part of the alternative replication protein A complex, aRPA, binds single-stranded DNA and probably plays a role in DNA repair. Compared to the RPA2-containing, canonical RPA complex, may not support chromosomal DNA replication and cell cycle progression through S-phase. The aRPA may not promote efficient priming by DNA polymerase alpha but could support DNA polymerase delta synthesis in the presence of PCNA and replication factor C (RFC), the dual incision/excision reaction of nucleotide excision repair and RAD51-dependent strand exchange. |
| Protein Name | Replication Protein A 30 Kda SubunitRp-A P30Replication Factor A Protein 4Rf-A Protein 4 |
| Database Links | Reactome: R-HSA-68962 |
| Cellular Localisation | NucleusLocalizes To Dna Repair Foci After Dna Damage |
| Alternative Antibody Names | Anti-Replication Protein A 30 Kda Subunit antibodyAnti-Rp-A P30 antibodyAnti-Replication Factor A Protein 4 antibodyAnti-Rf-A Protein 4 antibodyAnti-RPA4 antibody |
Information sourced from Uniprot.org